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Peli1 (rel)ieves autoimmunity

Nature Immunology volume 12, pages 927929 (2011) | Download Citation

T cell tolerance is essential to the prevention of autoimmunity. The ubiquitin E3 ligase Peli1 acts as a negative regulator of T cell activation and contributes to the maintenance of self-tolerance.

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References

  1. 1.

    , , & Nature 435, 590–597 (2005).

  2. 2.

    et al. Nat. Immunol. 12, 1002–1009 (2011).

  3. 3.

    & Annu. Rev. Immunol. 27, 693–733 (2009).

  4. 4.

    , , , & Immunity 31, 921–931 (2009).

  5. 5.

    Trends Immunol. 30, 33–42 (2009).

  6. 6.

    , & Nat. Immunol. 10, 1089–1095 (2009).

  7. 7.

    et al. Proc. Natl. Acad. Sci. USA 106, 4584–4590 (2009).

  8. 8.

    et al. Biochem. J. 434, 537–548 (2009).

  9. 9.

    et al. Nat. Immunol. 7, 1057–1065 (2006).

  10. 10.

    Cancer Res. 70, 3009–3012 (2011).

  11. 11.

    et al. J. Biol. Chem. 279, 37436–37444 (2004).

Download references

Author information

Affiliations

  1. Paul N. Moynagh is with the Institute of Immunology, National University of Ireland Maynooth, Maynooth, Ireland.

    • Paul N Moynagh

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Paul N Moynagh.

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DOI

https://doi.org/10.1038/ni.2108

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