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NUR who? An orphan transcription factor holds promise for monomaniacs

Nature Immunology volume 12, pages 727729 (2011) | Download Citation

The generation of Ly6C patrolling monocytes requires the transcription factor NR4A1 (Nur77). This finding provides insight into the development and function of these blood-resident cells.

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Author information

Affiliations

  1. Derek W. Cain is in the Department of Immunology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.

    • Derek W Cain
  2. Michael D. Gunn is in the Division of Cardiology and Department of Immunology, Duke University Medical Center, Durham, North Carolina, USA.

    • Michael D Gunn

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Michael D Gunn.

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DOI

https://doi.org/10.1038/ni.2074

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