New data show that the interferon-induced gene product IFIT1 is a sensor for 5′-triphosphorylated RNA of viral origin and that it functions within a larger IFIT complex to inhibit viral replication.
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Katie Vicari
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Ablasser, A., Hornung, V. Where, in antiviral defense, does IFIT1 fit?. Nat Immunol 12, 588–590 (2011). https://doi.org/10.1038/ni.2061
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DOI: https://doi.org/10.1038/ni.2061
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