At the end of the Eocene epoch, permanent ice cover developed over Antarctica as the Earth began to cool from greenhouse warmth. Sediment records off the Antarctic coast show spikes in weathering rate at the onset of ice growth that may indicate synchronous consumption of atmospheric carbon dioxide.
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Haley, B. Weathering away warmth. Nature Geosci 6, 86–87 (2013). https://doi.org/10.1038/ngeo1714
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DOI: https://doi.org/10.1038/ngeo1714