Figure 3: Comparison of measurable phenotypes between two subclasses in human and mouse HCC. | Nature Genetics

Figure 3: Comparison of measurable phenotypes between two subclasses in human and mouse HCC.

From: Application of comparative functional genomics to identify best-fit mouse models to study human cancer

Figure 3

(a) Cell proliferation index as measured by immunohistochemical staining with antibodies to PCNA (mouse) and to Ki-67 (human). Values shown are mean ± s.e. per 100 cells counted. (b) Apoptosis index, measured as the number of apoptotic cells per 100 cells counted. (c) Ubiquitination index, as measured by immunohistochemical staining with antibody to ubiquitin. Values shown are mean ± s.e. per 100 cells counted. P values were calculated by applying two sample t-test from each comparison.