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In genetic control of disease, does 'race' matter?

Nature Geneticsvolume 36pages12431244 (2004) | Download Citation

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As geneticists begin to identify gene variants associated with common diseases and responses to treatment, it is increasingly important to determine whether these variants have consistent effects across different 'racial' or 'ethnic' groups. Until recently, too little was known about either disease genetics or pharmacogenetics to make a detailed assessment. Now, a new study reviewing 43 disease-associated gene variants suggests that the effects of gene variants may be largely consistent across different 'racial' or 'ethnic' groups.

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Affiliations

  1. Department of Biology at Galton Labs, University College London, London, WC1E 6BT, UK

    • David B Goldstein
  2. Divisions of Genetics and Endocrinology at Children's Hospital/Harvard Medical School, Boston, 02115, Massachusetts, USA

    • Joel N Hirschhorn
  3. Program in Medical and Population Genetics, Broad Institute of MIT and Harvard University, Boston, Massachusetts, USA

    • Joel N Hirschhorn

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https://doi.org/10.1038/ng1204-1243

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