Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Genome-wide association studies coming of age in rice

Nature Genetics volume 42, pages 926–927 (2010)Cite this article

Subjects

A new study reports the next-generation sequencing of 517 rice genomes, each to approximately onefold coverage. By leveraging sequence information across rice lines and by imputing missing genotypes, a haplotype map (HapMap) was constructed and used for genome-wide association studies in this major crop.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Constructing a rice HapMap for GWAS with low-fold sequencing.

Marina Corral

References

  1. Harjes, C.E. et al. Science 319, 330–333 (2008).

    Article  CAS  Google Scholar 

  2. Myles, S. et al. Plant Cell 21, 2194–2202 (2009).

    Article  CAS  Google Scholar 

  3. Huang, X. et al. Nat. Genet. 42, 961–967 (2010).

    Article  CAS  Google Scholar 

  4. Manolio, T.A. et al. Nature 461, 747–753 (2009).

    Article  CAS  Google Scholar 

  5. Bentley, D.R. et al. Nature 456, 53–59 (2008).

    Article  CAS  Google Scholar 

  6. Ossowski, S. et al. Genome Res. 18, 2024–2033 (2008).

    Article  CAS  Google Scholar 

  7. Mather, K.A. et al. Genetics 177, 2223–2232 (2007).

    Article  CAS  Google Scholar 

  8. McNally, K.L. et al. Proc. Natl. Acad. Sci. USA 106, 12273–12278 (2009).

    Article  CAS  Google Scholar 

  9. Yu, J. et al. Nat. Genet. 38, 203–208 (2006).

    Article  CAS  Google Scholar 

  10. Atwell, S. et al. Nature 465, 627–631 (2010).

    Article  CAS  Google Scholar 

  11. Clark, R.M. et al. Science 317, 338–342 (2007).

    Article  CAS  Google Scholar 

  12. Hinds, D.A. et al. Science 307, 1072–1079 (2005).

    Article  CAS  Google Scholar 

  13. Weigel, D. & Mott, R. Genome Biol. 10, 107 (2009).

    Article  Google Scholar 

  14. Cronn, R. et al. Nucleic Acids Res. 36, e122 (2008).

    Article  Google Scholar 

  15. Huang, X. et al. Genome Res. 19, 1068–1076 (2009).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Richard M. Clark is at the Department of Biology, University of Utah, Salt Lake City, Utah, USA.,

    Richard M Clark

Authors
  1. Richard M Clark
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Richard M Clark.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Clark, R. Genome-wide association studies coming of age in rice. Nat Genet 42, 926–927 (2010). https://doi.org/10.1038/ng1110-926

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng1110-926

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing