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Photoreceptors in evolution and disease

A new study identifies the gene that, when mutated, causes autosomal recessive retinitis pigmentosa 25 (arRP25). The RP25 gene encodes an ortholog of Drosophila spacemaker (eyes shut), thus emphasizing common biological functions between Drosophila sensory systems and the human eye.

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Figure 1: A comparison of Drosophila and human retinas.


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Cook, B., Zelhof, A. Photoreceptors in evolution and disease. Nat Genet 40, 1275–1276 (2008).

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