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Wilms tumor and constitutional epigenetic defects

Nature Genetics volume 40, pages 1272–1273 (2008)Cite this article

Constitutional epigenetic defects affecting the 11p15.5 imprinted region cause a number of syndromic conditions involving birth defects. Now, an analysis of a large cohort of individuals with nonsyndromic Wilms tumor demonstrates the presence of known and newly identified constitutional IGF2-H19 imprinting defects, extending the phenotype associated with soma-wide 11p15.5 imprinting disorders.

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Authors and Affiliations

  1. Andrea Riccio is at the Department of Environmental Science, Second University of Naples, Caserta 81100, Italy and at the Institute of Genetics and Biophysics A. Buzzati-Traverso, CNR, Naples 80131, Italy. andrea.riccio@unina2.it,

    Andrea Riccio

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  1. Andrea Riccio
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Riccio, A. Wilms tumor and constitutional epigenetic defects. Nat Genet 40, 1272–1273 (2008). https://doi.org/10.1038/ng1108-1272

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