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Aging and cancer: killing two birds with one worm

Two new studies explore the genetic mechanisms connecting aging and tumor growth in Caenorhabditis elegans. This work should provide a basis to consider ways to prevent and treat age-dependent cancers.

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Figure 1: FOXO/DAF-16 regulates a coordinated program of genes that regulate tumor growth in C. elegans.

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Brunet, A. Aging and cancer: killing two birds with one worm. Nat Genet 39, 1306–1307 (2007). https://doi.org/10.1038/ng1107-1306

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