Two new studies explore the genetic mechanisms connecting aging and tumor growth in Caenorhabditis elegans. This work should provide a basis to consider ways to prevent and treat age-dependent cancers.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Pinkston, J.M., Garigan, D., Hansen, M. & Kenyon, C. Science 313, 971–975 (2006).
Pinkston-Gosse, J.M. & Kenyon, C. Nat. Genet. 39, 1403–1409 (2007).
Kenyon, C. Cell 120, 449–460 (2005).
Francis, R., Maine, E. & Schedl, T. Genetics 139, 607–630 (1995).
Paik, J.H. et al. Cell 128, 309–323 (2007).
Hu, M.C. et al. Cell 117, 225–237 (2004).
Di Cristofano, A., Pesce, B., Cordon-Cardo, C. & Pandolfi, P.P. Nat. Genet. 19, 348–355 (1998).
Nemoto, S., Fergussin, M.M. & Finkel, T. Science 306, 2105–2108 (2004).
You, H. et al. Proc. Natl. Acad. Sci. 101, 14057–14062 (2004).
Chen, Z. et al. Nature 436, 725–730 (2005).
Levine, B. Nature 446, 745–747 (2007).
Campisi, J. Cell 120, 513–522 (2005).
Matheu, A. et al. Nature 448, 375–379 (2007).
Finkel, T., Serrano, M. & Blasco, M.A. Nature 448, 767–774 (2007).
Murphy, C. et al. Nature 424, 277–283 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Brunet, A. Aging and cancer: killing two birds with one worm. Nat Genet 39, 1306–1307 (2007). https://doi.org/10.1038/ng1107-1306
Issue Date:
DOI: https://doi.org/10.1038/ng1107-1306
