Differences among dog breeds provide unique opportunities for studying the genetics of behavior, morphology and complex disease. Two new studies demonstrate how the unique evolutionary history of domestic dogs is particularly well suited to analysis by genome-wide association.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Anonymous. J. Hered. 36, 142 (1945).
Wright, S. J. Hered. 9, 87–90 (1918).
Lindblad-Toh, K. et al. Nature 438, 803–819 (2005).
Karlsson, E.K. et al. Nat. Genet. 39, 1321–1328 (2007).
Salmon Hillbertz, N.H.C. et al. Nat. Genet. 39, 1318–1320 (2007).
International HapMap Consortium. Nature 437, 1299–1320 (2005).
Sutter, N.B. et al. Genome Res. 14, 2388–2396 (2004).
Goding, C.R. Genes Dev. 14, 1712–1728 (2000).
Cattanach, B. J. Small Anim. Pract. 40, 193–200 (1999).
Ostrander, E.A. & Wayne, R.K. Genome Res. 15, 1706–1716 (2005).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Barsh, G. How the dog got its spots. Nat Genet 39, 1304–1306 (2007). https://doi.org/10.1038/ng1107-1304
Issue Date:
DOI: https://doi.org/10.1038/ng1107-1304
This article is cited by
-
First International Symposium “Epigenetic Control of Skin Development and Regeneration”: How Chromatin Regulators Orchestrate Skin Functions
Journal of Investigative Dermatology (2013)