A new study shows that during transcription, the TH2 interleukin gene cluster is organized into several small chromatin loops connected at their base by the protein SATB1. This first detailed glimpse of chromatin folding provides a new perspective on the coordination of cell type–specific gene expression.
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Göndör, A., Ohlsson, R. Transcription in the loop. Nat Genet 38, 1229–1230 (2006). https://doi.org/10.1038/ng1106-1229
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DOI: https://doi.org/10.1038/ng1106-1229
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Comparative analysis of cis-regulation following stroke and seizures in subspaces of conserved eigensystems
BMC Systems Biology (2010)