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Genome-wide tagging for everyone

Nature Genetics volume 38, pages 1227–1228 (2006)Cite this article

The recently completed International HapMap Project has provided detailed information about patterns of genetic variation in four different population samples. Two new studies show that the patterns of variation documented in the HapMap can be applied to other human populations, suggesting it is time to establish a standardized platform for all whole-genome association studies.

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Figure 1: The two determinants of tag transferability are proximity between the reference and target populations and, more importantly, the amount of association between variants (LD) in the target population.

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Authors and Affiliations

  1. Institute for Genome Sciences and Policy, Center for Population Genomics and Pharmacogenetics, Duke University, Durham, 27710, North Carolina, USA

    Anna C Need & David B Goldstein

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  1. Anna C Need
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  2. David B Goldstein
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Need, A., Goldstein, D. Genome-wide tagging for everyone. Nat Genet 38, 1227–1228 (2006). https://doi.org/10.1038/ng1106-1227

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