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High Oct-ane fuel powers the stem cell

Nature Genetics volume 29, pages 246–247 (2001)Cite this article

The Oct4 transcription factor has a critical role in the maintenance of pluripotent stem cells in an undifferentiated state and in the formation of mammalian germ cells. Recent work demonstrates that a specific nuclear receptor is involved in regulating the expression of Oct4 itself. This finding has important implications for understanding pluripotent stem-cell biology and nuclear reprogramming.

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  1. Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, 19107, Pennsylvania, USA

    Peter J. Donovan

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  1. Peter J. Donovan
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Donovan, P. High Oct-ane fuel powers the stem cell. Nat Genet 29, 246–247 (2001). https://doi.org/10.1038/ng1101-246

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