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Microarray databases: standards and ontologies

Nature Genetics volume 32, pages 469473 (2002) | Download Citation

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Abstract

A single microarray can provide information on the expression of tens of thousands of genes. The amount of information generated by a microarray-based experiment is sufficiently large that no single study can be expected to mine each nugget of scientific information. As a consequence, the scale and complexity of microarray experiments require that computer software programs do much of the data processing, storage, visualization, analysis and transfer. The adoption of common standards and ontologies for the management and sharing of microarray data is essential and will provide immediate benefit to the research community.

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Acknowledgements

We thank A. Brazma, H. Parkinson and S. Sansone for critically reading the manuscript.

Author information

Affiliations

  1. Center for Bioinformatics and Department of Genetics, University of Pennsylvania, 423 Guardian Drive, Philadelphia, Pennsylvania 19104-6021, USA.

    • Christian J. Stoeckert Jr
  2. Clinical Sciences Centre/Imperial College Microarray Centre, Imperial College, Hammersmith Campus, Du Cane Road, London W12 ONN, UK.

    • Helen C. Causton
  3. Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5120, USA.

    • Catherine A. Ball

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Christian J. Stoeckert Jr.

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DOI

https://doi.org/10.1038/ng1028