The availability of the complete genomic sequence of yeast now enables elucidation of molecular mechanisms governing gene expression patterns. New results from the yeast genome and recent advances in predicting and finding human promoters support the use of similar combinatorial approaches to study genome-wide transcriptional regulation in humans.
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Werner, T. The promoter connection. Nat Genet 29, 105–106 (2001). https://doi.org/10.1038/ng1001-105
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DOI: https://doi.org/10.1038/ng1001-105
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