Defining the molecular nature of the genetic risk of psychiatric disorders has been notoriously difficult. Now, a flurry of genome-wide association studies for schizophrenia and bipolar disorder provides preliminary evidence for replicated signals.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Common alleles contribute to schizophrenia in CNV carriers
Molecular Psychiatry Open Access 22 September 2015
-
Prediction of susceptibility to major depression by a model of interactions of multiple functional genetic variants and environmental factors
Molecular Psychiatry Open Access 27 March 2012
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Chanock, S.J. & Hunter, D.J. Nature 452, 537–538 (2008).
Ferreira, M.A.R. et al. Nat. Genet. 40, 1056–1058 (2008).
O'Donovan, M.C. et al. Nat. Genet. 40, 1053–1055 (2008).
Ioannidis, J.P., Patsopoulos, N.A. & Evangelou, E. PLoS ONE 2, e841 (2007).
Wang, W.Y., Barratt, B.J., Clayton, D.G. & Todd, J.A. Nat. Rev. Genet. 6, 109–118 (2005).
Reich, D.E. & Lander, E.S. Trends Genet. 17, 502–510 (2001).
Sebat, J. et al. Science 316, 445–449 (2007).
Walsh, T. et al. Science 320, 539–543 (2008).
Xu, B. et al. Nat. Genet. 40, 880–885 (2008).
Roy, M.A., Walsh, D. & Kendler, K.S. Acta Psychiatr. Scand. 93, 224–234 (1996).
Stefansson, H. et al. Nature advance online publication, 10.1038/nature07229 (30 July 2008).
The International Schizophrenia Consortium. Nature advance online publication, 10.1038/nature07239 (30 July 2008).
Bassett, A.S., Chow, E.W. & Weksberg, R. Am. J. Med. Genet. 97, 45–51 (2000).
Kendler, K.S. & Diehl, S.R. Schizophr. Bull. 19, 261–285 (1993).
Hemminki, K., Forsti, A. & Bermejo, J.L. PLoS ONE 3, e2504 (2008).
Sullivan, P.F., Kendler, K.S. & Neale, M.C. Arch. Gen. Psychiatry 60, 1187–1192 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Maher, B., Riley, B. & Kendler, K. Psychiatric genetics gets a boost. Nat Genet 40, 1042–1044 (2008). https://doi.org/10.1038/ng0908-1042
Issue Date:
DOI: https://doi.org/10.1038/ng0908-1042
This article is cited by
-
The role of READ1 and KIAA0319 genetic variations in developmental dyslexia: testing main and interactive effects
Journal of Human Genetics (2017)
-
Common alleles contribute to schizophrenia in CNV carriers
Molecular Psychiatry (2016)
-
Prediction of susceptibility to major depression by a model of interactions of multiple functional genetic variants and environmental factors
Molecular Psychiatry (2012)
-
Psychiatric Molecular Genetics and the Ethics of Social Promises
Journal of Bioethical Inquiry (2011)
-
A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication
Molecular Psychiatry (2010)
