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A haplotype map for the laboratory mouse

Two reports present detailed analyses of the haplotype structure of widely used laboratory mice based on resequencing data from 15 inbred strains. The studies provide the deepest view thus far of the patterns of genetic variation segregating in the inbred lines, and have implications for the design of complex trait mapping studies in mice.

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Figure 1: The genetic variation between these three classical inbred strains of mice is explained by the variation observed between wild-derived inbred strains.

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Mott, R. A haplotype map for the laboratory mouse. Nat Genet 39, 1054–1056 (2007). https://doi.org/10.1038/ng0907-1054

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