Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Alu: a parasite's parasite?

The technical problem of detecting the retrotransposition—amplification and genomic dispersion of sequences through an RNA intermediate—of Pol III–directed transcripts has been solved. This provides a long-sought experimental system to learn how Alu repeats amplified to a high copy number in human DNA.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Co-compartmentalization of Alu RNA and LINE1 mRNA with cis-acting ORF2p.

Erin Boyle

References

  1. Lander, E.S. et al. Nature 409, 860–921 (2001).

    Article  CAS  Google Scholar 

  2. Dewannieux, M., Esnault, C. & Heidmann, T. Nat. Genet. 35, 41–48 (2003).

    Article  CAS  Google Scholar 

  3. Rubin, C.M. et al. Nature 284, 372–374 (1980).

    Article  CAS  Google Scholar 

  4. Kajikawa, M. & Okada, N. Cell 111, 433–444 (2002).

    Article  CAS  Google Scholar 

  5. Jurka, J. Proc. Natl. Acad. Sci. USA 94, 1872–1877 (1997).

    Article  CAS  Google Scholar 

  6. Boeke, J.D. Nat. Genet. 16, 6–7 (1997).

    Article  CAS  Google Scholar 

  7. Sarrowa, J., Chang, D.Y. & Maraia, R.J. Mol. Cell Biol. 17, 1144–1151 (1997).

    Article  CAS  Google Scholar 

  8. Li, T-H. et al. Gene 239, 367–372 (1999).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schmid, C. Alu: a parasite's parasite?. Nat Genet 35, 15–16 (2003). https://doi.org/10.1038/ng0903-15

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng0903-15

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing