Several devastating genetic diseases illustrate that peroxisomes are essential to the development and functioning of the central nervous system. New work using a mouse model now shows that peroxisome integrity in oligodendrocytes is essential for axonal maintenance.
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Aubourg, P. Axons need glial peroxisomes. Nat Genet 39, 936–938 (2007). https://doi.org/10.1038/ng0807-936
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