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Axons need glial peroxisomes

Several devastating genetic diseases illustrate that peroxisomes are essential to the development and functioning of the central nervous system. New work using a mouse model now shows that peroxisome integrity in oligodendrocytes is essential for axonal maintenance.

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Figure 1: Oligodendrocyte peroxisomes.


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Aubourg, P. Axons need glial peroxisomes. Nat Genet 39, 936–938 (2007).

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