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Target mimics modulate miRNAs

Nature Genetics volume 39, pages 935–936 (2007)Cite this article

A 23-nucleotide sequence conserved in species from rice to Arabidopsis thaliana in a family of noncoding RNAs resembles a cleavable miRNA target site—but not exactly. A new study demonstrates that the site is not cleaved and instead negatively regulates miRNA activity through mimicry.

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Figure 1: Possible models of how the induction of the Pi deprivation response in plants is regulated by an miRNA and its target mimic.

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Authors and Affiliations

  1. Daniel H. Chitwood and Marja C. P. Timmermans are in the Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA. timmerma@cshl.edu,

    Daniel H Chitwood & Marja C P Timmermans

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  1. Daniel H Chitwood
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  2. Marja C P Timmermans
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Chitwood, D., Timmermans, M. Target mimics modulate miRNAs. Nat Genet 39, 935–936 (2007). https://doi.org/10.1038/ng0807-935

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