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The 1993–94 Généthon human genetic linkage map

Nature Genetics volume 7, pages 246–339 (1994)Cite this article

Abstract

In 1992, we described a second-generation genetic linkage map of the human genome. Using 1,267 new microsatellite markers, we now present a new genetic linkage map containing a total of 2,066 (AC)n short tandem repeats, 60% of which show a heterozygosity of over 0.7. Statistical linkage analysis based on the genotyping of eight large CEPH families placed these markers in the 23 linkage groups. The map includes 1,266 intervals and spans a total distance of 3690 centiMorgans (cM). A total of 1,041 markers could be ordered with odds ratios greater than 1000:1. About 56% of this map is at a distance of 1 cM or less from one of its markers.

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Author information

Affiliations

  1. Généthon, 1 rue de l'Internationale, 91000, Evry, France

    Gabor Gyapay, Jean Morissette, Alain Vignal, Colette Dib, Cécile Fizames, Philippe Millasseau, Sophie Marc & Jean Weissenbach

  2. Centre d'Etudes du Polymorphismne Humain, 27 rue Juliette Dodu, 75010, Paris, France

    Gabor Gyapay & Philippe Millasseau

  3. Réseau de Médecine Génétique, Centre Hospitalier de I'Université Laval, Québec, Canada

    Jean Morissette

  4. Laboratoire de Génétique Moléculaire, Institut Jacques Monod, 2 place Jussieu, 75005, Paris, France

    Giorgio Bernardi

  5. INSERM U 358, 27 rue Juliette Dodu, 75010, Paris, France

    Mark Lathrop

  6. Unité de Génétique Moléculaire Humaine, CNRS URA 1445, Institut Pasteur, 75724, Paris Cédex, France

    Jean Weissenbach

Authors
  1. Gabor Gyapay
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  2. Jean Morissette
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  3. Alain Vignal
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  4. Colette Dib
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  5. Cécile Fizames
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  6. Philippe Millasseau
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  7. Sophie Marc
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  8. Giorgio Bernardi
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  9. Mark Lathrop
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  10. Jean Weissenbach
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Gyapay, G., Morissette, J., Vignal, A. et al. The 1993–94 Généthon human genetic linkage map. Nat Genet 7, 246–339 (1994). https://doi.org/10.1038/ng0694supp-246

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  • DOI: https://doi.org/10.1038/ng0694supp-246

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