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The hippocratic finger points the blame at PGE2

Digital clubbing has been recognized since the time of the ancient Greeks as a sign of systemic disease. Now, a new study identifies a role for prostaglandin E2 in the pathogenesis of digital clubbing observed in familial hypertrophic osteoarthropathy.

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Sarah R. Keilson

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Coggins, K., Coffman, T. & Koller, B. The hippocratic finger points the blame at PGE2. Nat Genet 40, 691–692 (2008). https://doi.org/10.1038/ng0608-691

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