Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Evolutionary conservation in myoblast fusion

The fusion of myoblasts into myofibers has been studied extensively in Drosophila, but it is not known if the same mechanisms operate in vertebrates. A new study suggests an unanticipated degree of similarity in zebrafish.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Syncytial fast muscles within a zebrafish embryo.

Bhylahalli Srinivas and Sudipto Roy

References

  1. Chen, E.H. & Olson, E.N. Trends Cell Biol. 14, 452–460 (2004).

    Article  CAS  Google Scholar 

  2. Horsley, V. & Pavlath, G.K. Cells Tissues Organs 176, 67–78 (2004).

    Article  Google Scholar 

  3. Srinivas, B.P., Woo, J., Leong, W.Y. & Roy, S. Nat. Genet. 39, 781–786 (2007).

    Article  CAS  Google Scholar 

  4. Kim, S. et al. Dev. Cell 12, 571–586 (2007).

    Article  CAS  Google Scholar 

  5. Massarwa, R., Carmon, S., Shilo, B.Z. & Schejter, E.D. Dev. Cell 12, 557–569 (2007).

    Article  CAS  Google Scholar 

  6. Hakeda-Suzuki, S. et al. Nature 416, 438–442 (2002).

    Article  CAS  Google Scholar 

  7. Luo, L., Liao, Y.J., Jan, L.Y. & Jan, Y.N. Genes Dev. 8, 1787–1802 (1994).

    Article  CAS  Google Scholar 

  8. Patari-Sampo, A., Ihalmo, P. & Holthofer, H. Ann. Med. 38, 483–492 (2006).

    Article  CAS  Google Scholar 

  9. Ochi, H. & Westerfield, M. Dev. Growth Differ. 49, 1–11 (2007).

    Article  CAS  Google Scholar 

  10. Galletta, B.J., Chakravarti, M., Banerjee, R. & Abmayr, S.M. Mech. Dev. 121, 1455–1468 (2004).

    Article  CAS  Google Scholar 

  11. Buckingham, M. Curr. Opin. Genet. Dev. 16, 525–532 (2006).

    Article  CAS  Google Scholar 

  12. Chen, E.H., Pryce, B.A., Tzeng, J.A., Gonzalez, G.A. & Olson, E.N. Cell 114, 751–762 (2003).

    Article  CAS  Google Scholar 

  13. Donoviel, D.B. et al. Mol. Cell. Biol. 21, 4829–4836 (2001).

    Article  CAS  Google Scholar 

  14. Sampaolesi, M. et al. Nature 444, 574–579 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Krauss, R. Evolutionary conservation in myoblast fusion. Nat Genet 39, 704–705 (2007). https://doi.org/10.1038/ng0607-704

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng0607-704

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing