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The multitasking genome

Nature Genetics volume 38, pages 608–609 (2006)Cite this article

The identification of hundreds of thousands of clusters of transcriptional start sites, many located within internal exons of protein-coding genes, indicates that promoter sites are common and that transcriptional organization is complex. This transcriptional architecture implies that most genomic regions serve multiple functions.

When is an exon not an exon?

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Figure 1: The conventional view of the genome is that protein-coding regions of the genome have few elements that serve more than one function (exon, intron, promoter, enhancer regions).

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  1. Affymetrix, Inc., 3380 Central Expressway, Santa Clara, 95051, California, USA

    Thomas R Gingeras

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  1. Thomas R Gingeras
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Gingeras, T. The multitasking genome. Nat Genet 38, 608–609 (2006). https://doi.org/10.1038/ng0606-608

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