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Antiviral synergism

Nature Genetics volume 37, pages 565–566 (2005)Cite this article

The restriction of herpesvirus by natural killer cells, initiated before the acquired immune response, illustrates the value of innate immune mechanisms for viral containment. Now, a new study shows that the activating natural killer cell receptor Ly49P and the major histocompatibility complex class I H-2Dk molecule act in concert to restrict mouse cytomegalovirus infection, identifying a new mechanism of host resistance.

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Figure 1: A model for Ly49-mediated recognition of virally infected targets by NK cells.

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  1. the National Cancer Institute, Frederick, 21702-1201, Maryland, USA

    Mary Carrington

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  1. Mary Carrington
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Carrington, M. Antiviral synergism. Nat Genet 37, 565–566 (2005). https://doi.org/10.1038/ng0605-565

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