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Methylation matters: a new spin on maspin

Nature Genetics volume 31, pages 123–124 (2002)Cite this article

The theory that DNA methylation controls tissue-specific gene expression has remained controversial despite being frequently cited for more than 25 years. A new study shows a pristine example of methylation and gene expression that is cell-type–restricted, although questions about causality persist.

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Authors and Affiliations

  1. Department of Neurological Surgery and UCSF Comprehensive Cancer Center, Brain Tumor Research Center, University of California, San Francisco, California, USA

    Joseph F. Costello

  2. Department of Radiation Oncology and the Winship Cancer Institute, Emory University, Atlanta, Georgia, USA

    Paula M. Vertino

Authors
  1. Joseph F. Costello
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  2. Paula M. Vertino
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Costello, J., Vertino, P. Methylation matters: a new spin on maspin. Nat Genet 31, 123–124 (2002). https://doi.org/10.1038/ng0602-123

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