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Chipping away at the genetics of smoking behavior

Three large consortia present comprehensive analyses that identify genetic factors influencing smoking initiation, intensity and cessation. The genetic architecture of these three phases of smoking behavior appears to be largely distinct.

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Figure 1: Smoking behavior as a multistep process with genetic influences.


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Correspondence to Christopher I Amos.

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Competing interests

P. Cinciripini has received grant support from Pfizer, which manufactures vrenicline (Chantrix).

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Amos, C., Spitz, M. & Cinciripini, P. Chipping away at the genetics of smoking behavior. Nat Genet 42, 366–368 (2010).

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