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Universal epistasis analysis

Nature Genetics volume 37, pages 457–458 (2005)Cite this article

Epistasis analysis is a foundation in the analysis of genetic networks, but in complex or poorly defined processes, defining the phenotype can be an insurmountable hurdle. A new study shows that microarray expression profiles can be used as a 'phenotype' for epistasis analysis of the development of a multicellular organism, offering a potentially universal solution to this problem.

Expression patterns as phenotypes

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Figure 1: Ordering pathways using epistasis analysis.

Katie Ris

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Affiliations

  1. the Banting and Best Department of Medical Research at the University of Toronto, Toronto, M5G 1L6, Ontario, Canada

    Timothy R Hughes

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  1. Timothy R Hughes
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Hughes, T. Universal epistasis analysis. Nat Genet 37, 457–458 (2005). https://doi.org/10.1038/ng0505-457

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  • DOI: https://doi.org/10.1038/ng0505-457

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