Human hemoglobin variants are known to protect the host against severe malaria due to P. falciparum. A new study demonstrates that such genetic variation may also be associated with increased transmission of this pathogen from the human host to the Anopheles vector.
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Pasvol, G. Protective hemoglobinopathies and Plasmodium falciparum transmission. Nat Genet 42, 284–285 (2010). https://doi.org/10.1038/ng0410-284