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Delivery codes for fly transgenics

Chromosomal position effects influence the transcription of exogenously introduced transgenes. A new study identifies molecular tools that exploit these properties to fine-tune transgenic gene expression through the use of site-specific integration and the gypsy insulator element.

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Figure 1: Drosophila larvae carrying Gal4 drivers that promote the expression of UAS::eGFP transgenes in specific tissues.

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Tubon, T., Yin, JP. Delivery codes for fly transgenics. Nat Genet 40, 383–384 (2008). https://doi.org/10.1038/ng0408-383

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  • DOI: https://doi.org/10.1038/ng0408-383

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