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The human promoter methylome

DNA methylation is a heritable epigenetic mark found in a wide range of eukaryotes. By mapping DNA methylation within the majority of human promoters, the authors of a new study uncover intriguing insights into genome evolution, cellular differentiation and potential links to tumorigenesis.

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Figure 1: DNA methylation in development and disease.

Kim Caesar

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Zilberman, D. The human promoter methylome. Nat Genet 39, 442–443 (2007). https://doi.org/10.1038/ng0407-442

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