News & Views | Published:

Fly meets shotgun: shotgun wins

Nature Genetics volume 24, pages 327328 (2000) | Download Citation

Subjects

The sequencing group at Celera Genomics Corporation has cooperated with the European, Canadian and American genome projects to demonstrate that a genomic sequence as large as that of Drosophila melanogaster euchromatin (120 Mb) can be obtained by assembling the sequence of random (‘shotgun’) clones without the prerequisite for a clone-based physical map.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    et al. Science 269, 496–512 (1995).

  2. 2.

    et al. Nature 377 (suppl.), 3– 174 (1995).

  3. 3.

    et al. Science 287, 2185– 2915 (2000).

  4. 4.

    et al. Science 287, 2196– 2204 (2000).

  5. 5.

    et al. Science 287, 2204– 2215 (2000).

  6. 6.

    et al. Science 287, 2216– 2218 (2000).

  7. 7.

    & Science 287, 2222–2224 (2000).

  8. 8.

    & Genome Res. 7, 401–409 (1997).

  9. 9.

    C. elegans Sequencing Consortium. Science 282, 2012–2018 ( 1998).

  10. 10.

    Proc. Natl Acad. Sci. USA 14, 714– 726 (1928).

  11. 11.

    Chromosome Maps of Drosophila (CRC Press, Boca Raton, Florida, 1991).

  12. 12.

    J. Hered. 29, 11–13 ( 1938).

  13. 13.

    et al. Science 246, 641–646 (1989).

  14. 14.

    , , & Proc. Natl Acad. Sci. USA 91, 6824– 6829 (1994).

  15. 15.

    & The Drosophila Genome Map: A Practical Guide (ed. Landes, R.G.) (Austin, Texas, 1995).

Download references

Author information

Affiliations

  1. Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge , Massachusetts 02138, USA.  dhartl@oeb.harvard.edu

    • Daniel L Hartl

Authors

  1. Search for Daniel L Hartl in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/74125

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing