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A genetic linkage map of the bovine genome

Nature Genetics volume 6, pages 227–235 (1994)Cite this article

Abstract

A cattle genetic linkage map was constructed which marks about 90% of the expected length of the cattle genome. Over 200 DNA polymorphisms were genotyped in cattle families which comprise 295 individuals in full sibling pedigrees. One hundred and seventy–one loci were found linked to one other locus. Twenty nine of the 30 chromosome pairs are represented by at least one of the 36 linkage groups. Less than a 50 cM difference was found in the male and female genetic maps. The conserved loci on this map show as many differences in gene order compared to humans as is found between humans and mice. The conservation is consistent with the patterns of karyotypic evolution found in the rodents, primates and artiodactyls. This map will be important for localizing quantitative trait loci and provides a basis for further mapping.

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Authors and Affiliations

  1. CSIRO, Division of Tropical Animal Production, Gehrmann Laboratories, University of Queensland, Brisbane, 4072, Australia

    W. Barendse, S.M. Armitage, D. Clayton, F. McCarthy, S.S. Moore & D.J.S. Hetzel

  2. Department of Physiology and Pharmacology, University of Georgia, 30602, USA

    L.M. Kossarek, W.M. Grosse & R.A. McGraw

  3. Department of Genetics, Hebrew University of Jerusalem, 91094, Israel

    A. Shalom & M. Soller

  4. Department of Meat and Animal Science, University of Wisconsin-Madison, 53706, USA

    B.W. Kirkpatrick

  5. Department of Veterinary Pathobiology and Center for Animal Genetics, Texas A&M University, Texas, 77843, USA

    A.M. Ryan, L. Li, H.L. Neibergs, N. Zhang, J. Weiss & J.E. Womack

  6. Department of Genetics, Trinity College, Dublin, Ireland

    P. Creighton

  7. Animal Genetics and Breeding Unit, Agricultural Research Organization, Bet-Dagan, 50-250, Israel

    M. Ron

  8. International Laboratory for Research on Animal Diseases, Nairobi, Kenya

    A.J. Teale

  9. lnstitut für Nutztierwissenschaften, ETH Zuerich, CH-8092, Switzerland

    R. Fries

  10. Genmark Inc., Salt Lake City, Utah, 84108, USA

    M. Georges

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  1. W. Barendse
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  2. S.M. Armitage
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Barendse, W., Armitage, S., Kossarek, L. et al. A genetic linkage map of the bovine genome. Nat Genet 6, 227–235 (1994). https://doi.org/10.1038/ng0394-227

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