The global patterning of histone lysine methylation has been scrutinized over the years in an effort to uncover unique features indicative of chromatin function. A study in Caenorhabditis elegans now shows that nucleosomes covering exons and introns on active genes are differentially marked by H3K36 trimethylation, suggesting a new mode of communication between chromatin and pre-mRNA processing.
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Sims III, R., Reinberg, D. Processing the H3K36me3 signature. Nat Genet 41, 270–271 (2009). https://doi.org/10.1038/ng0309-270
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DOI: https://doi.org/10.1038/ng0309-270
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