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Enhancing genome annotation with chromatin

A new approach that scans the modification states of histones along the chromosome allows the identification of enhancer elements in the complex genomes of higher eukaryotes. This is an important step in the functional annotation of the genome.

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Figure 1: Graphical representation of a stretch of genomic DNA wrapped around nucleosomes.

Katie Ris

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Schübeler, D. Enhancing genome annotation with chromatin. Nat Genet 39, 284–285 (2007). https://doi.org/10.1038/ng0307-284

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