Like most organisms, yeast has relatively few genes that are necessary for viability. The presence of a duplicate gene elsewhere in the genome underpins many cases of dispensability. A new study suggests that the backup mechanism is more complex than previously assumed and requires feedback loops that ensure transcriptional upregulation of the duplicate.
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Hurst, L., Pál, C. Dissecting dispensability. Nat Genet 37, 214–215 (2005). https://doi.org/10.1038/ng0305-214
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DOI: https://doi.org/10.1038/ng0305-214
