Although a first draft of the human genome is now available, our knowledge of the set of transcripts expressed from this sequence is still far from complete. A new method using ink-jet microarray technology to experimentally test predicted exons provides a genome-based platform for gene identification that bypasses an important limitation of older technologies based on cDNA libraries.
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Burge, C. Chipping away at the transcriptome. Nat Genet 27, 232–234 (2001). https://doi.org/10.1038/85772
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DOI: https://doi.org/10.1038/85772