A large number of bacterial artificial chromosomes containing human DNA have been regionally mapped to chromosomes and are available to investigators. This dense collection of BACs (about 2.6 clones per Mb) will enhance the diagnostic capabilities of genomic abnormalities.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
http://ncbi.nlm.nih.gov/genome/seq/HsHome.shtml
Osoegawa, K. et al. Genomics 52, 1–8 (1998).
The BAC Resource Consortium Nature 409, 953–958 (2001).
Korenberg, J.R. et al. Genome Res. 9, 994–1001 (1999).
Cheung, V.G. et al. Genome Res. 9, 989–993 (1999).
Kirsch, I.R. et al. Nature Genet. 24, 339–340 (2000).
Leversha, M.A., Dunham, I. & Carter, N.P. Chromosome Res. 7, 571–573 (1999).
Lejeune, J., Gautier, M. & Turpin, R. C.R. Acad. Sci. 248, 1721–1722 (1959).
Woodward, K., Kendall, E., Vetrie, D. & Malcolm, S. Am. J. Hum. Genet. 63, 207–217 (1998).
Lupski, J.R. et al. Cell 66, 219–232 (1991).
Scambler, P.J. et al. Lancet 339, 1138–1139 (1992).
Ewart, A.K. et al. Nature Genet. 5, 11–16 (1993).
Solinas-Toldo, S. et al. Genes Chromosomes Cancer 20, 399–407 (1997).
Pinkel, D. et al. Nature Genet. 20, 207–211 (1998).
Lakich, D., Kazazian, H.H.J., Antonarakis, S.E. & Gitschier, J. Nature Genet. 5, 236–241 (1993).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Antonarakis, S. BACking up the promises. Nat Genet 27, 230–232 (2001). https://doi.org/10.1038/85769
Issue Date:
DOI: https://doi.org/10.1038/85769