The international consortium to sequence the human genome is using a clone-by-clone approach to DNA sequencing. The large arrays of clones that have been created for this purpose are important not only for the Human Genome Project: as our understanding of the individual and population variation of our genome becomes deeper, these clones will become important sequenced exemplars of human genes, with substantial implications for future research.
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Little, P. The end of all human DNA maps?. Nat Genet 27, 229–230 (2001). https://doi.org/10.1038/85766
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DOI: https://doi.org/10.1038/85766