A new study identifies mutations in the HR gene as the cause of Marie Unna hereditary hypotrichosis (MUHH). The mutations seem to disrupt an unusual leader sequence–based mechanism of translational repression, making MUHH the first example of a disease linked to this form of repression.
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Weiner, L., Brissette, J. Hair lost in translation. Nat Genet 41, 141–142 (2009). https://doi.org/10.1038/ng0209-141
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DOI: https://doi.org/10.1038/ng0209-141