Many organisms have an amazing capacity to adapt to conditions of low oxygen, but the cellular mechanisms of this are poorly understood. A new study in mice has unveiled a molecular trigger that initiates a cascade of events to reprogram cellular oxygen requirements.
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Kelly, D. Hypoxic reprogramming. Nat Genet 40, 132–134 (2008). https://doi.org/10.1038/ng0208-132
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DOI: https://doi.org/10.1038/ng0208-132
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