Genes of the Major Histocompatibility Complex (MHC) are extraordinarily diverse. MHC variants influence many important biological traits, including immune recognition, susceptibility to infectious and autoimmune diseases, individual odors, mating preferences, kin recognition, cooperation and pregnancy outcome. The MHC story now becomes even more complex with the demonstration that human females prefer odors from males carrying allelic matches to their own paternally inherited MHC genes.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset
BMC Genomics Open Access 10 November 2010
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Jacob, S., McClintock, M.K., Zelano, B. & Ober, C. Nature Genet . 30, 175–179 (2002).
Carrington M. et al. Science 283, 1748–1752 (1999).
McMichael, A.J. & Phillips, R.E. Annu. Rev. Immunol. 15, 271–296 (1997).
Ober, C. et al. Am. J. Hum. Genet. 61, 497–504 (1997).
Boyse, E.A., Beauchamp, G.K., Bard, J. & Yamazaki, K. in Psychoneuroimmunology Vol. 2 (eds Ader, R., Felten, D.L. & Cohen, N.) 831–845 (Academic, London, 1990).
Potts, W.K., Manning, C.J. & Wakeland, E.K. Nature 352, 619–621 (1991).
Landry, C., Garant, D., Duchesne, P. & Bernatchez, L. Proc. R. Soc. Lond. B Biol. Sci. 268, 1279–1285. (2001).
Reusch, T., Haeberli, M.A., Aeschlimann, P.B. & Milinski, M. Nature 414, 300–302 (2001).
Penn, D. & Potts, W. Am. Nat. 153, 145–164 (1999).
Manning, C.J., Wakeland, E.K. & Potts, W.K. Nature 360, 581–583 (1992).
Meagher, S., Penn, D.J. & Potts, W.K. Proc. Natl Acad. Sci. U.S.A. 97, 3324–3329 (2000).
Wedekind, C., Seebeck, T., Bettens, F. & Paepke, A. Proc. R. Soc. Lond. B 260, 245–249 (1995).
Carroll, L.S., Penn, D.J. & Potts, W.K. Proc. Natl Acad. Sci. USA (in the press).
Montag, S. et al. Proc. Natl Acad. Sci. USA 98, 9249–9254 (2001).
Wedekind, C. & Füri, S. Proc. R. Soc. Lond. B 264, 1471–1479 (1997).
Yamazaki, K. et al. Science 240, 1331–1332 (1988).
Penn, D. & Potts, W. Proc. R. Soc. London. B 265, 1299–1306 (1998).
Isles, A.R., Baum, M.J., Ma, D., Keverne, E.B. & Allen, N.D. Nature 409, 783–784 (2001).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Potts, W. Wisdom through immunogenetics. Nat Genet 30, 130–131 (2002). https://doi.org/10.1038/ng0202-130
Issue Date:
DOI: https://doi.org/10.1038/ng0202-130
