A bird's eye view of global methylation

Abstract

Restriction landmark genomic scanning applied to a broad variety of cancer types can disclose tumour-specific and tumour-type–specific global methylation profiles. This and other genome-scanning approaches allows the rapid analysis of methylation profiles of thousands of genes in parallel—and promises to identify new genes critical to carcinogenesis and other biological processes.

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Eng, C., Herman, J. & Baylin, S. A bird's eye view of global methylation. Nat Genet 24, 101–102 (2000). https://doi.org/10.1038/72730

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