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Coiled-coils and motile cilia

Genetic mapping studies in dogs, mice, zebrafish and humans have identified two new genes required for the assembly of motile cilia. The resulting gene products, CCDC39 and CCDC40, may represent previously unidentified components of the dynein regulatory complex.

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Figure 1: Comparison of normal and CCDC39-deficient cilia.

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Correspondence to Peter Satir.

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Satir, P. Coiled-coils and motile cilia. Nat Genet 43, 10–11 (2011). https://doi.org/10.1038/ng0111-10

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