Genetic mapping studies in dogs, mice, zebrafish and humans have identified two new genes required for the assembly of motile cilia. The resulting gene products, CCDC39 and CCDC40, may represent previously unidentified components of the dynein regulatory complex.
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References
Afzelius, B.A. Science 193, 317–319 (1976).
Nonaka, S. et al. Cell 95, 829–837 (1998).
Hirokawa, N. et al. Cell 125, 33–45 (2006).
Zariwala, M.A., Knowles, M.R. & Omran, H. Annu. Rev. Physiol. 69, 423–450 (2007).
Avidor-Reiss, T. et al. Cell 117, 527–539 (2004).
Merveille, A.-C. et al. Nat. Genet. 43, 72–78 (2011).
Becker-Heck, A. et al. Nat. Genet. 43, 79–84 (2011).
Heuser, T. et al. J. Cell Biol. 187, 921–933 (2009).
Fliegauf, M., Benzing, T. & Omran, H. Nat. Rev. Mol. Cell Biol. 8, 880–893 (2007).
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Satir, P. Coiled-coils and motile cilia. Nat Genet 43, 10–11 (2011). https://doi.org/10.1038/ng0111-10
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DOI: https://doi.org/10.1038/ng0111-10