Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Copy-number analysis goes more than skin deep

Accurate measurements of genomic copy number polymorphisms are required to define their medical relevance, but obtaining such measurements for multiallelic copy number variants has been challenging. A copy-number study of psoriasis now sets some useful precedents for a maturing field.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1

Image courtesy of Joost Schalkwijk

References

  1. Hollox, E.J. et al. Nat. Genet. 40, 23–25 (2008).

    Article  CAS  Google Scholar 

  2. Selsted, M.E. et al. J. Biol. Chem. 268, 6641–6648 (1993).

    CAS  PubMed  Google Scholar 

  3. Niyonsaba, F. et al. Immunology 111, 273–281 (2004).

    Article  CAS  Google Scholar 

  4. Candille, S.I. et al. Science 318, 1418–1423 (2007).

    Article  CAS  Google Scholar 

  5. Redon, R. et al. Nature 444, 444–454 (2006).

    Article  CAS  Google Scholar 

  6. Stranger, B.E. et al. Science 315, 848–853 (2007).

    Article  CAS  Google Scholar 

  7. Clayton, D.G. et al. Nat. Genet. 37, 1243–1246 (2005).

    Article  CAS  Google Scholar 

  8. Altshuler, D. et al. Nat. Genet. 26, 76–80 (2000).

    Article  CAS  Google Scholar 

  9. Gonzalez, E. et al. Science 307, 1434–1440 (2005).

    Article  CAS  Google Scholar 

  10. Aitman, T.J. et al. Nature 439, 851–855 (2006).

    Article  CAS  Google Scholar 

  11. Fanciulli, M. et al. Nat. Genet. 39, 721–723 (2007).

    Article  CAS  Google Scholar 

  12. Yang, Y. et al. Am. J. Hum. Genet. 80, 1037–1054 (2007).

    Article  CAS  Google Scholar 

  13. Perry, G.H. et al. Nat. Genet. 39, 1256–1260 (2007).

    Article  CAS  Google Scholar 

  14. de Jongh, G.J. et al. J. Invest. Dermatol. 125, 1163–1173 (2005).

    Article  CAS  Google Scholar 

  15. Lande, R. et al. Nature 449, 564–569 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

McCarroll, S. Copy-number analysis goes more than skin deep. Nat Genet 40, 5–6 (2008). https://doi.org/10.1038/ng0108-5

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng0108-5

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing