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References
Adler, D.A. et al. Proc. Natl. Acad. Sci. USA 94, 9244–9248 (1997).
Nguyen, D.K. & Disteche, C.M. Nat. Genet. 38, 47–53 (2006).
Xiong, Y. et al. Nat. Genet. 42, 1043–1047 (2010).
Mukherjee, A.S. & Beermann, W. Nature 207, 785–786 (1965).
Alekseyenko, A.A., Larschan, E., Lai, W.R., Park, P.J. & Kuroda, M.I. Genes Dev. 20, 848–857 (2006).
Gilfillan, G.D. et al. Genes Dev. 20, 858–870 (2006).
Pan, Q., Shai, O., Lee, L.J., Frey, B.J. & Blencowe, B.J. Nat. Genet. 40, 1413–1415 (2008).
Wang, E.T. et al. Nature 456, 470–476 (2008).
Mortazavi, A., Williams, B.A., McCue, K., Schaeffer, L. & Wold, B. Nat. Methods 5, 621–628 (2008).
Kim, H. et al. Nat. Med. 16, 804–808 (2010).
Gregg, C. et al. Science 329, 643–648 (2010).
Lercher, M.J., Urrutia, A.O. & Hurst, L.D. Nat. Genet. 31, 180–183 (2002).
Deng, X. et al. Nat. Genet. 43, 1179–1185 (2011).
Acknowledgements
We thank M. Kuroda, E. Larschan, M. Gelart, C. Wang and J. Lee for helpful discussions and a critical reading of the manuscript.
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Kharchenko, P., Xi, R. & Park, P. Evidence for dosage compensation between the X chromosome and autosomes in mammals. Nat Genet 43, 1167–1169 (2011). https://doi.org/10.1038/ng.991
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DOI: https://doi.org/10.1038/ng.991
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