Supplementary Figure 7: Copy number analysis of EGFR-mutant lung adenocarcinoma tumor specimens from patients. | Nature Genetics

Supplementary Figure 7: Copy number analysis of EGFR-mutant lung adenocarcinoma tumor specimens from patients.

From: Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

Supplementary Figure 7

Each panel represents allele specific floating point copy number state profile for an individual sample for all autologous chromosomes. Arm level GISTIC events for lung adenocarcinoma are indicated on relevant chromosomal arms by the background color, red for a significant arm gain, blue for a significant arm loss. Genes of interest are annotated along the bottom of each panel. Regions of chromosomal loss or gain were determined by analysis of whole-exome sequencing (see Online Methods) of the indicated samples as described in Figure 5. Cancer-related genes in regions of copy-number gain of ≥ than 1.5X ploidy (Blue) or copy-number loss of ≤ 0.5X ploidy (Red) are indicated.

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