Supplementary Figure 4: Effects of detectable cfDNA alterations on overall survival. | Nature Genetics

Supplementary Figure 4: Effects of detectable cfDNA alterations on overall survival.

From: Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

Supplementary Figure 4

(a-d) Forest plots assessing the effects of indicated cfDNA detectable gene and pathway alterations on OS. (a-b) Effect of gene level (a) and pathway level (b) alterations on OS in response to EGFR TKI treatment. HR with 95% CI and p-values determined by Cox-proportional regression test (methods). (c-d) Effect of gene level (c) and pathway level (d) alterations on OS in response to osimertinib treatment. HR with 95% CI and p-values determined by Cox-proportional regression test (Online Methods).

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